WP2 - Interactions of the influenza virus RNA polymerase with host factors

Partners involved:
N° 5, Dr. Ervin Fodor (WP Leader)
N° 1, Prof. Otto Haller
N° 6, Dr. Nadia Naffakh

Objectives
The aim of WP2 is to identify crucial host factors that interact with the influenza virus RNA polymerase complex. There is increasing evidence that the RNA polymerase is a crucial determinant of viral host range and pathogenicity, which suggests that there is a differential interaction between host factors and RNA polymerases in different hosts. Our aim is to identify these host factors and elucidate their role in the processes of viral RNA synthesis.

WPs